KCC2 downregulation facilitates epileptic seizures
نویسندگان
چکیده
منابع مشابه
Psychogenic non-epileptic seizures.
Psychogenic non-epileptic seizures (PNES) need to be differentiated from epileptic seizures as the management varies for both. Presence of tongue biting, falling and urinary incontinence favors a diagnosis of epileptic seizures. We report two children with features suggestive of epileptic seizures that were eventually diagnosed as PNES with the help of video-EEG monitoring.
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For almost 40 years, neuroscientists thought that epileptic seizures began abruptly, just a few seconds before clinical attacks. There is now mounting evidence that seizures develop minutes to hours before clinical onset. This change in thinking is based on quantitative studies of long digital intracranial electroencephalographic (EEG) recordings from patients being evaluated for epilepsy surge...
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In this study, the effect of an experimentally increased excitability in hippocampal neurons, via hippocampal kindling, on amygdala kindling rate was investigated in rats. Animals were divided into 4 groups. In all groups, except group 2, tripolar electrodes were implanted in the amygdala and CAI region of the dorsal hippocampus. Group 2 animals were only implanted with tripolar electrodes in...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2017
ISSN: 2045-2322
DOI: 10.1038/s41598-017-00196-7